Yehezkel Ben-Ari

Bumetanide for autism: more eye contact, less amygdala activation

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Bumetanide for autism: more eye contact, less amygdala activation Nouchine Hadjikhani (Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, Etats-Unis et Université de Gothenburg, Gothenburg, Suède), Eric Lemonnier (Centre Hospitalier Universitaire, Limoges, France) et Yehezkel Ben-Ari (Neurochlore, Marseille, France) One of the permanent features of autistic patients is the fear of looking at the … Read more

Childbirth and the multiple facets of a hormone : oxytocin

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The birth process took millions of years to be developed. It must allow 4 major reactions: a passage from an immunologically protected environment to the external environment, the acquisition of microbes in its digestive system, the transition from a temperature of 38 ° to colder external temperatures and especially the evacuation of the water molecules … Read more

Plea for biomedical innovation

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A large part of the therapeutic applications of biomedical research is generated in innovation incubators. More than 70% of new drugs come from discoveries made by small structures close to academic research, which have a greater capacity for innovation than larger companies. These ones invest in start-ups by buying them or acquiring licenses. With a … Read more

Alert! Finkielkraut is suffering from acute Muslimis/Arabis

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This is a brain syndrome that has genetic and environmental links with Stockholm syndrome; the same acute manifestations of paranoia, headaches, the hibernation of the cortical structures involved in reasoning, and an unhealthy attraction to a group / population that is being loathed. This is at the root of every problem: women complain – the … Read more

Pax Americana, female orgasm and autism

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The case is emblematic of the protectionism of the US authorities. A German company discovers a product that would have a beneficial effect on female orgasm. After expensive but successful trials, it asks the Food and Drug Administration (FDA) authorities for a US marketing authorization. The 28 experts of the commission reject it, arguing that … Read more

Technology is a useful servant but a dangerous master

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The Paper of Yves Frégnac in Science raises major issues that are on the convergence of the paucity of concepts in science, the evaluation and financing of scientific investigations and the false promises of big programs to understand the brain and treat neurological and psychiatric disorders. The incredible acceleration of technological advances attested every day … Read more

Scientific fraud: when «publish or perish » leads to the distortion of reality

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The increase of scientific frauds and publications that are not reproductible is a major concern that has been analyzed many times. So-called leading journals have more and more retractations, articles considered major and opening up new perspectives are abandoned because based on tampered or “arranged” results, even emanating from prestigious laboratories. These frauds, however, have … Read more

Why is it so hard to reform scientific research?

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In a refreshing article, an American scientist proposes a series of changes to improve the functioning of the National Institutes of Health (NIH), one of the leading scientific research institutions in the US. Despite the differences in the organization of science in the US and Europe, it is interesting to note the similarity in the criticisms … Read more

Sanofi and the case of the sodium valproate

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Overwhelming testimonies about the Sanofi and health officials disaster on the case of sodium valproate The dangers of this molecule has been known for at least 3 decades, resulting in life-long sequelae of children with autism, delayed development, drug-resistant epilepsy seizures, etc. These emotional and overwhelming testimonies show both the importance of the commitment of … Read more

Two articles establish the link between in utero development, inflammation, microbiota and autism

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Since the classical work of the late Paul Patterson, it is known that the activation of the immune system during the intrauterine period produces an autistic syndrome by activating the immune system and causing the release of inflammatory molecules such as interleukins which will impact the cerebral maturation. It is also known that in rodents … Read more

The false promises of Artificial Intelligence and the genuine issue of poverty and brain mal development

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According to some, immortality is for tomorrow and the baby who is going to live 1000 years already born. There are now singularity universities, and the popes of this trend are relying on a heavy mixture of science fiction and prophecies. R. Kurzweil for instance has decided that the evolution will reach its climax in … Read more

The pseudo-scientific vision of the evolution reviewed by the preachers of Artificial Intelligence

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Artificial intelligence is trendy, it is invested with every virtues and vices/dangers. According to some people, there it is, happiness is tomorrow with immortality in support of it, and a sort of graft between human being and machine/robot living in the Garden of Eden. The reading of these “theses” and defenders illustrates perfectly how science … Read more

The posthumous assassinations of Margaret Thatcher

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Deregulations are weapons that sometimes kill decades later. Thus, in the 1980s, when Mrs Thatcher deregulates sanitary controls and, above all, facilitates the conditions required to feed cows from animal carcasses (no need to boil completely and for long periods of time), it will lead years later to the crisis of mad cow disease with … Read more

For people with autism, avoiding eye contact could be due to something other than indifference

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Individuals with autism spectrum disorder (ASD) often find it difficult to look others in the eyes, and we don’t exactly know why. What could be granted for indifference could actually have a completely different explanation. Indeed, according to Nouchine Hadjikhani, cofounder of Neurochlore and director of the Neurolimbic Research Laboratory in the Martinos Center in … Read more

Successful Phase 2B for a clinical trial

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Autism is a complex neurodevelopmental disorder that affects about one in 100 children, with a prevalence four times higher in boys. The causes of this disorder remain unknown to date and no drug therapy is available. Treatment is only symptomatic and requires personalized educational therapies. We have been working for several years on the mechanism … Read more

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Alternative truth in Science: when Stalin, Putin and Trump see eye to eye

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When religion or politicians have a say on scientific issues, science is agonizing and of course when there is a combination of both the adverse events are exponentially enhanced. We all have in mind Trofim Denissovitch Lyssenko who denied any validity to Mendel’s and Morgan’s genetics considered as not materialistic and unreliable that had to be … Read more

Europe is drowning!

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The recent populist trend of most European countries and the irrational opposition to immigrants is more than immoral; it is a major blow to our civilisation. It is in contradiction with our principles /constitution. The belief that democracy is a superior value and system is not readily compatible with tens of thousands of immigrants families, kids, babies … Read more

The dilemma of the pain in the newborn

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  Curiously we know a lot on pain of the mother during delivery but much less that of the new born. Several techniques and drugs can infirm the biblical saying –thou shall deliver in pain –and that is of course important. Yet, we should not forget that the partner of this incredibly complex event, namely … Read more

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