In my previous articles, I discussed the limitations of genetics in explaining autism and the importance of environmental factors—particularly pesticides during pregnancy. I then addressed the complex issue of epigenetics—the environmental regulation of gene activation or inactivation—an essential process that does not involve changes to the DNA sequence. This is a “non-sequential” form of control, … Read more
More than 250 years ago, Linnaeus observed changes in floral symmetry that were passed down through several generations. Two centuries later, it was discovered that this change was not due to a genetic mutation but rather to genetic regulation mediated by what has since been termed epigenesis—the factors that control the activation or inactivation of … Read more
In a previous chapter, I illustrated how pesticides can affect brain development and lead to autism. Here, before continuing the discussion of the long list of factors that can lead to the same outcomes, I’ll revisit the key principles of brain maturation to better understand how these factors come into play and result in developmental … Read more
As I wrote in a previous blog post, Autism Spectrum Disorders (ASDs) “originate” in utero, as we demonstrated five years ago. By retrospectively analyzing data collected in maternity wards (more than 150 non-genetic parameters) using machine learning, we can identify at birth nearly half of the babies who will have autism and all those who will … Read more
In our article published in the *Journal of Medical Genetics*, Etienne Danchin and I addressed the issue of genetics dominating the field of autism. Our aim was to challenge the simplistic claims found in the scientific literature and mainstream media—that “autism is X% genetic” (often cited as 80%!). While it is true that a small … Read more
For several years now, I have been working with my colleagues on treatments for autism and various brain diseases and tumors based on the loss of brain inhibition. At the heart of this system is the regulation of intracellular concentrations of various ions, particularly chloride levels. As I have summarized many times, these levels largely … Read more
Gaza has existed since ancient times, with a history spanning more than 4,000 years. An important commercial center, particularly during the Phoenician era, it served as a key stopover and was a prosperous city while Jerusalem was still in its formative stages and, at best, a small town. Occupied by the Philistines, the Assyrians, the … Read more
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