AN ANSWER TO ERWAN BÉZARD

Following the recent publication of a paper called “GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease“, Erwan Bézard, director of the Neurodégénérative Diseases Institute of Bordeauxpublished a commentary, that you can find here. Here’s our answer: First of all, we always pay attention to discussions and criticisms and we welcome … Read more

An answer to Prof Tepper about his short comment on our recently published paper

We recently published a paper called “GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson disease“. Prof Tepper briefly commented it on Twitter. Here’s our answer:   Our paper is not some sort of “artefact”. Things are never so simple, they usually have an explanation. The devil, as we all know, … Read more

Bumetanide strikes again in the arena of neurological disorders: a novel therapeutic approach to treat Parkinson’s disease

A new study led by Prs. Yehezkel Ben-Ari & Constance Hammond (Neurochlore and B&A Therapeutics, Marseille, France) demonstrates that bumetanide, an antagonist of the NKCC1 chloride importer, normalizes the activity of neurons in the striatum and alleviates motor impairment in a mouse model of Parkinson’s disease. These findings corroborate the results of a pilot clinical … Read more

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