Bumetanide strikes again in the arena of neurological disorders: a novel therapeutic approach to treat Parkinson’s disease
A new study led by Prs. Yehezkel Ben-Ari & Constance Hammond (Neurochlore and B&A Therapeutics, Marseille, France) demonstrates that bumetanide, an antagonist of the NKCC1 chloride importer, normalizes the activity of neurons in the striatum and alleviates motor impairment in a mouse model of Parkinson’s disease. These findings corroborate the results of a pilot clinical … Read more
