How does a Benzodiazepine produce a transient awakening of patients under severe long-lasting comatose state due to heavy brain lesions ?

Awakening, a temporary revival of patients who have been akinetic, apathic and with no reaction for years following a large brain damage, has been observed after administration of drugs, but the mechanisms underlying them remain unknown. In a recent study, Arnst et al. report spectacular effects of Zolpidem on a 29 years old patient after … Read more

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